Adriana-Alina Rus, PhD student
. "New panel of biomarkers to discriminate between amelanotic and melanotic metastatic melanoma", Frontiers in oncology 12: 1061832, (2023)
doi: doi: 10.3389/fonc.2022.1061832
IF: 5.74AI: 1.15
This project aims to understand the molecular events associated with protein aggregation and how a Golgi located protein along with the UPR pathway modulate this process. Model proteins such as IL-1β and α-synuclein, previously shown to aggregate will be employed for these studies. Achieving the objectives of this project should facilitate the understanding of the signaling pathways and the sequence of events correlating the stress sensing machinery with cytoplasmic proteome instability.