Aura-Elena Ionescu, PhD
Group: Cell Signaling Research
Department: EnzymologyScientific Researcher
Research interests: G protein-coupled receptors (GPCRs),
Signaling pathways in cancer,
Mass spectrometry,
Protein expression and purification.
Biography
Born: 19th of November 1988, Ploiesti, Romania 2003 - 2007: „Ion Luca Caragiale” National College, Ploieşti, Romania 2007- 2012: Faculty of Pharmacy at University of Medicine and Pharmacy "Carol Davila" Bucharest 2012 - now: Institute of Biochemistry of the Romanian Academy
Papers
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. "Synthesis and characterization of a novel [52Mn]Mn-labelled affibody based radiotracer for HER2+ targeting", Inorganic Chemistry Frontiers, (2023)
doi: 10.1039/D3QI00356F
IF: 7.78AI: 1.01 -
. "Trojan horse treatment based on PEG-coated extracellular vesicles to deliver doxorubicin to melanoma in vitro and in vivo", Cancer biology & therapy 23(1): 1-16, (2022)
doi: 10.1080/15384047.2021.2003656
IF: 4.74 -
. "Regulation of TRPM8 channel activity by Src-mediated tyrosine phosphorylation", Journal of Cellular Physiology 235(6): 5192-5203, (2020)
IF: 4.52AI: 1.50 -
. "Analysis of EYA3 Phosphorylation by Src Kinase Identifies Residues Involved in Cell Proliferation", International Journal of Molecular Sciences 20(24): 6307, (2019)
IF: 4.18 -
. "WDR1 is a novel EYA3 substrate and its dephosphorylation induces modifications of the cellular actin cytoskeleton", Scientific reports 8(1): 2910, (2018)
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. "Expression, Purification, and Kinetic Analysis of PTP Domains", Methods in molecular biology (Clifton, N.J.) 1447: 39-66, (2016)
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. "Phosphoketolases from Lactococcus lactis, Leuconostoc mesenteroides and Pseudomonas aeruginosa: Dissimilar sequences, similar substrates but distinct enzymatic characteristics", Applied Microbiology and Biotechnology 18(98): 7855-67, (2014)
IF: 3.34 -
. "RAG and HMGB1 create a large bend in the 23RSS in the V(D)J recombination synaptic complexes", Nucleic Acids Research 41(4): 2437-2454, (2013)
IF: 8.81AI: 3.40 -
. "Synthesis and Biological Evaluation of Some New N1-[4-(4-Chlorophenylsulfonyl) benzoyl]- N4-(aryl)-thiosemicarbazides and Products of Their Cyclization", Synthesis and Biological Evaluation of Some New N -[4-(4-Chlorophenylsulfonyl) benzoyl]- N -(aryl)-thiosemicarbazides and Products of Their Cyclization 24(4): 309-321, (2013)
doi: DOI 10.1002/hc.21095
IF: 1.26 -
. "Expression, Purification, and Kinetic Analysis of PTP Domains", pp 39- 66, Protein Tyrosine Phosphatases, Rafael Pulido, (2016).
ISBN: 978-1-4939-3744-8
Grants
No grants.