Romanian Academy
Carmen Alexandra Tanase, Dr.
Group: Enzymology
Department: EnzymologyResearcher
Research interests: Molecular mechanisms of multivesicular bodies biogenesis and transport. Exosomes biogenesis, secretion, uptake, and role in normal and pathological states.
Discovery of new anti-metastasic and anti-Alzheimer's disease drugs.
Biography
Ph.D. University of Missouri-Kansas City, Dept. Molecular Biology and Biochemistry, 2001. Protein import into mitochondria
Post-doc. Kansas University-Medical Center, Dept. Cell Biology and Anatomy, 2001-2004. Role of extracellular matrix proteins in early vertebrate development and diabetic kidney
Independent researcher. Institute of Biochemistry, 2005-present. Role of protein tyrosine phosphatases and Bro1 domain- containing proteins in cell-cell communication and signal transduction.
Post-doc. Kansas University-Medical Center, Dept. Cell Biology and Anatomy, 2001-2004. Role of extracellular matrix proteins in early vertebrate development and diabetic kidney
Independent researcher. Institute of Biochemistry, 2005-present. Role of protein tyrosine phosphatases and Bro1 domain- containing proteins in cell-cell communication and signal transduction.
Papers
- . Histidine domain-protein tyrosine phosphatase interacts with Grb2 and GrpL. PloS one, 2010, 5(12):e14339.IF=4.41
- . Analysis of molecular determinants of PRL-3. Journal of cellular and molecular medicine, 2009, 13(9B):3141-50.
- . Differences in expression pattern and function between zebrafish hoxc13 orthologs: recruitment of Hoxc13b into an early embryonic role. Developmental biology, 2004, 274(2):318-33.
- . The expression of tissue inhibitor of metalloproteinase 2 (TIMP-2) is required for normal development of zebrafish embryos. Dev Genes, 2003, 8(213):382-9.