Norica Nichita, Dr.

Biography

Papers

• Alina-Veronica Ghionescu, Mihaela Uta, Andrei Sorop, Catalin Lazar, Petruta R. Flintoaca-Alexandru, Gabriela Chiritoiu, Livia Sima, Stefana-Maria Petrescu, Simona Olimpia Dima, Norica NichitaAlina-Veronica Ghionescu et al . "The endoplasmic reticulum degradation-enhancing α-mannosidase-like protein 3 attenuates the unfolded protein response and has pro-survival and pro-viral roles in hepatoma cells and hepatocellular carcinoma patients", Journal of Biomedical Science 32, (2025)
  doi: https://doi.org/10.1186/s12929-024-01103-9
  IF: 9.00AI: 2.30
• Caras I, Ionescu I-E, Pantazica A-M, van Eerde A, Steen H, Heldal I, Haugslien S, Tucureanu C, Chelmus R-E, Tofan V-C, Costache A, Onu A, Su H, Nichita N, Liu-Clarke J and Stavaru CCaras I et al . "Humanized mouse model reveals the immunogenicity of Hepatitis B Virus vaccine candidates produced in CRISPR/Cas9-edited Nicotiana benthamiana", Frontiers Immunology 16: 1479689, (2025)
  doi: https://doi.org/10.3389/fimmu.2025.1479689
  IF: 5.70AI: 1.60
• Hammel A, Cucos, LM, Caras I, Popescu CI, Stavaru C, Nichita N, Bock R.Hammel A et al . "The red alga Porphyridium as a host for molecular farming: Efficient production of immunologically active hepatitis C virus glycoprotein", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 121(24), (2024)
  doi: DOI10.1073/pnas.2400145121
  IF: 9.40AI: 4.30
• Hang Su, André van Eerde, Espen Rimstad, Ralph Bock, Norica Nichita, Igor A Yakovlev, Jihong Liu ClarkeHang Su et al . "Plant-made vaccines against viral diseases in humans and farm animals", Frontiers in Plant Science(14:1170815), (2023)
  doi: 10.3389/fpls.2023.1170815
  IF: 6.20AI: 1.10
• David PATRICHE, Mirela POPESCU, Costin-Ioan POPESCU, Norica NICHITADavid PATRICHE et al . "CLASS II PHOSPHATIDYLINOSITOL 3-KINASE 2ß IS A NOVEL TARGET FOR THE POTENTIAL DEVELOPMENT OF ANTIVIRAL DRUGS AGAINST THE HEPATITIS B VIRUS", Farmacia 70(2): 266-271, (2022)
  IF: 1.40
• Dobrica MO, van Eerde A, Tucureanu C, Onu A, Paruch L, Caras I, Vlase E, Steen H, Haugslien S, Alonzi D, Zitzmann N, Bock R, Dubuisson J, Popescu CI, Stavaru C, Liu Clarke J, Branza-Nichita NDobrica MO et al . "Hepatitis C virus E2 envelope glycoprotein produced in Nicotiana benthamiana triggers humoral response with virus-neutralizing activity in vaccinated mice", Plant Biotechnology Journal: 1-13, (2021)
  IF: 13.20
• Craciunescu O, Icriverzi M, Florian PE, Roseanu A, Trif M.Craciunescu O et al . "Mechanisms and Pharmaceutical Action of Lipid Nanoformulation of Natural Bioactive Compounds as Efficient Delivery Systems in the Therapy of Osteoarthritis", Pharmaceutics 8(13): 1108, (2021)
  IF: 6.32
• Nedelcu I, Jipa R, Vasilescu R, Băicuș C, Popescu CI, Manea E, Stoichițoiu L, Pinte L, Damalan A, Simulescu O, Stoica I, Stoica M, Hristea ANedelcu I et al . "Long-Term Longitudinal Evaluation of Six Commercial Immunoassays for the Detection of IgM and IgG Antibodies against SARS CoV-2", Viruses 6(13): 1244, (2021)
  IF: 5.00
• Pantazica AMM, Cucos LM, Stavaru C, Liu Clarke J, Branza-Nichita NPantazica AMM et al . "Challenges and Prospects of Plant-Derived Oral Vaccines against Hepatitis B and C Viruses", Plants 10(10): 1-17, (2021)
  IF: 4.60
• Riva L, Spriet C, Barois N, Popescu CI, Dubuisson J, Rouillé YRiva L et al . "Comparative Analysis of Hepatitis C Virus NS5A Dynamics and Localization in Assembly-Deficient Mutants", Pathogens (Basel, Switzerland) 10(2), (2021)
  IF: 3.49
• Dobrica MO, Lazar C, Nichita N*Dobrica MO et al . "N-Glycosylation and N-Glycan Processing in HBV Biology and Pathogenesis", Cells 6(9), (2020)
  IF: 5.60
• Codruta C. Popescu, Marius C. Stoian, Lia-Maria Cucos, Anca G. Coman, Antonio Radoi, Anca Paun, Niculina D. H˘adade, Arnaud Gautier, Costin-Ioan Popescu and Mihaela MatacheCodruta C. Popescu et al . "A polycarboxylic chelating ligand for efficient resin purification of His-tagged proteins expressed in mammalian systems", RSC Advances(10): 23931–23935, (2020)
  IF: 3.04
• Dobrica Mihaela-Olivia, Catalin Lazar, Norica NichitaDobrica Mihaela-Olivia et al . "Production of Chimeric Hepatitis B Virus Surface Antigens in Mammalian Cells", Methods in Molecular Biology, Blaine Pfeifer and Andrew Hill (eds.). Springer Science. 2183(Vaccine Delivery Technology: Methods and Protocols), (2020)
  
• Ion GND, Nitulescu GM, Popescu CI.Ion GND et al . "Targeting TRAIL", Bioorg Med Chem Lett 18(29): 2527-2534, (2019)
  IF: 2.45
• Dobrica MO, Lazar C, Paruch L, van Eerde A, Clarke JL, Tucureanu C, Caras I, Ciulean S, Onu A, Tofan V, Branzan A, Urban S, Stavaru C, Branza-Nichita NDobrica MO et al . "Oral administration of a chimeric Hepatitis B Virus S/preS1 antigen produced in lettuce triggers infection neutralizing antibodies in mice", Vaccine 36(38): 5789-5795, (2018)
  IF: 3.27
• Dobrica MO, Lazar C, Nichita N*Dobrica MO et al . "N-Glycosylation and N-Glycan Processing in HBV Biology and Pathogenesis", Cells 6(9): https://doi.org/10.3390/cells9061404, (2017)
  IF: 5.60
• Uta M, Sima LE, Hoffmann P, Dinca V, Branza-Nichita NUta M et al . "Development of a DsRed-expressing HepaRG cell line for real-time monitoring of hepatocyte-like cell differentiation by fluorescence imaging, with application in screening of novel geometric microstructured cell growth substrates", Biomedical microdevices 19(1): 3, (2017)
  IF: 2.08AI: 0.70
• Vlaicu O, Selescu T, Pastrama F, Munteanu C, Riva L, Dubuisson J, Rouille Y, Popescu CIVlaicu O et al . "Novel replicons and trans-encapsidation systems for Hepatitis C Virus proteins live imaging and virus-host interaction proteomics", Journal of virological methods 246: 42-50, (2017)
  
• Clarke JL, Paruch L, Dobrica MO, Caras I, Tucureanu C, Onu A, Ciulean S, Stavaru C, Eerde A, Wang Y, Steen H, Haugslien S, Petrareanu C, Lazar C, Popescu CI, Bock R, Dubuisson J, Branza-Nichita NClarke JL et al . "Lettuce-produced hepatitis C virus E1E2 heterodimer triggers immune responses in mice and antibody production after oral vaccination", Plant biotechnology journal 15(12): 1611-1621, (2017)
  
• Lazar C, Uta M, Petrescu SM, Branza-Nichita NLazar C et al . "Novel function of the endoplasmic reticulum degradation-enhancing α-mannosidase-like proteins in the human hepatitis B virus life cycle, mediated by the middle envelope protein", Cellular microbiology 19(2), (2017)
  
• Florian PE, Rouillé Y, Ruta S, Nichita N, Roseanu AFlorian PE et al . "Recent advances in human viruses imaging studies", Journal of basic microbiology 56(6): 591-607, (2016)
  
• Florian PE, Macovei A, Lazar C, Milac AL, Sokolowska I, Darie CC, Evans RW, Roseanu A, Branza-Nichita NFlorian PE et al . "Characterization of the anti-HBV activity of HLP1-23, a human lactoferrin-derived peptide", Journal of medical virology 85(5): 780-8, (2013)
  IF: 2.22AI: 0.70
• Lazar C, Macovei A, Petrescu S, Branza-Nichita NLazar C et al . "Activation of ERAD pathway by human hepatitis B virus modulates viral and subviral particle production", PloS one 7(3): e34169, (2012)
  IF: 3.73AI: 1.50
• Florian P, Macovei A, Sima L, Nichita N, Mattsby-Baltzer I, Roseanu AFlorian P et al . "Endocytosis and trafficking of human lactoferrin in macrophage-like human THP-1 cells (1)", Biochemistry and cell biology = Biochimie et biologie cellulaire 90(3): 449-55, (2012)
  IF: 2.92
• Pollock S, Nichita NB, Böhmer A, Radulescu C, Dwek RA, Zitzmann N.Pollock S et al . "Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells", Proc Natl Acad Sci U S A. 104(40): 17176-81, (2008)
  IF: 9.50
• Raducanu A, Stoica C, Icriverzi M, Lazar C, Nichita N, Roseanu A.Raducanu A et al . "Antiviral activity of lactoferrin against bovine viral diarrhea virus", Romanian Jornal of Biochemistry(42): 21-29, (2005)
  
• Branza-Nichita N, Petrescu AJ, Negroiu G, Dwek RA, Petrescu SMBranza-Nichita N et al . "N-glycosylation processing and glycoprotein folding-lessons from the tyrosinase-related proteins", Chemical reviews 100(12): 4697-712, (2000)
  
• Petrescu SM, Branza-Nichita N, Negroiu G, Petrescu AJ, Dwek RAPetrescu SM et al . "Tyrosinase and glycoprotein folding: roles of chaperones that recognize glycans", Biochemistry 39(18): 5229-37, (2000)
  
• Branza-Nichita N, Negroiu G, Petrescu AJ, Garman EF, Platt FM, Wormald MR, Dwek RA, Petrescu SMBranza-Nichita N et al . "Mutations at critical N-glycosylation sites reduce tyrosinase activity by altering folding and quality control", The Journal of biological chemistry 275(11): 8169-75, (2000)
  
• Negroiu G, Branza-Nichita N, Costin GE, Titu H, Petrescu AJ, Dwek RA, Petrescu SMNegroiu G et al . "Investigation of the intracellular transport of tyrosinase and tyrosinase related protein (TRP)-1. The effect of endoplasmic reticulum (ER)-glucosidases inhibition", Cellular and molecular biology (Noisy-le-Grand, France) 45(7): 1001-10, (1999)
  
• Negroiu G, Branza-Nichita N, Petrescu AJ, Dwek RA, Petrescu SMNegroiu G et al . "Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells", The Biochemical journal 344 Pt 3: 659-65, (1999)
  

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