The project is agreed as a joint collaboration among IBAR, ATOMKI and UD, the latter being a cost free participant. There are two main directions envisaged by the proposed project: - receptors mapping and therapy, using an affibody against HER2 receptors, combined with an adequate radioisotope. In this respect, the specific objectives are: a) expression and purification of affibodies; b) establishing labelling procedures; c) ex vivo and/or in vivo testing of optimal compounds.
Head of Department
Professor Dr. Stefan Eugen Szedlacsek is the Head of the Enzymology Department at the Institute of Biochemistry of the Romanian Academy. He holds a PhD degree in Biotechnology from Polytechnic University of Bucharest as well as a MSc in Organic Synthesis (Polytechnic University- Bucharest) and MSc in Mathematics (Bucharest University). As a visiting scientist, he performed research in the field of cholesterol metabolism University of Illinois at Urbana-Champaign (USA), where he succeeded to evidence a new pathway in the metabolism of oxysterols. He is an “Alexander von Humboldt“ fellow and worked in Germany, in the Institute of Biochemistry (Kiel University) More...
Research Assistant
Adina-Gabriela Puiu is a researcher in the Institute of Biochemistry of the Romanian Academy. Adina-Gabriela is currently working in Enzymology in the Enzymology.
Andra-Elena Cosoreanu is a researcher in the Institute of Biochemistry of the Romanian Academy. Andra-Elena is currently working in Enzymology in the Enzymology.
Research Assistant
Andrei-Mihai Vasilescu is a researcher in the Institute of Biochemistry of the Romanian Academy. Andrei-Mihai is currently working in Enzymology in the Enzymology.
Asistent
Bica Constantin Catalin is a researcher in the Institute of Biochemistry of the Romanian Academy. Bica is currently working in Enzymology in the Enzymology.
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10 may 2023: Seminar IBAR
1. Lecture title: "Labelling anti-HER2-affibodies with 52Mn via pyclen based bifunctional ligands: from ligand to in vivo PET/MR experiments"
-Balazs Varadi, PhD(c), Department of Physical Chemistry, Faculty of Science and Technology, University of Debrecen, Hungary, Institute for Nuclear Research, Debrecen, Hungary.
2. Lecture title: "Designing macrocyclic ligands for biomedical application"
-Professor Gyula Tircso, PhD, Department of Physical Chemistry, Faculty of Science and Technology, University of Debrecen, Hungary.
Romanian Academy